Duc-Hanh T. Nguyen

Researcher Profile 5/10

University of Medicine and Pharmacy at Ho Chi Minh City · Biology

11 publications · 812 citations · h-index 8

Information

🏛️Affiliation: University of Medicine and Pharmacy at Ho Chi Minh City
🔬Field: Biology
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An h-index of 8 places this researcher in Biology, within the top 25% of 3,752 profiles in this field in our directory.

Featured publications

Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants259 citations
Science · 2003 · DOI

Dominant-Negative Inhibitors of Soluble TNF Attenuate Experimental Arthritis without Suppressing Innate Immunity to Infection161 citations
The Journal of Immunology · 2007 · DOI

A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens104 citations
mAbs · 2011 · DOI

Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody93 citations
Journal of Allergy and Clinical Immunology · 2012 · DOI

A robust heterodimeric Fc platform engineered for efficient development of bispecific antibodies of multiple formats68 citations
Methods · 2018 · DOI

Engineering Fully Human Monoclonal Antibodies from Murine Variable Regions52 citations
Journal of Molecular Biology · 2010 · DOI

Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function44 citations
Blood · 2012 · DOI

Clinical Significance of Circulating DNA Microsatellite Markers in Plasma of Melanoma Patients25 citations
Annals of the New York Academy of Sciences · 2000 · DOI

Abstract 1860: Bispecific claudin-6 x CD3 antibodies in a 2 + 1 format demonstrate selectivity and activity on human ovarian cancer cells6 citations
Cancer Research · 2021 · DOI

Abstract 1743: IL12 heterodimeric Fc-fusions engineered for reduced potency exhibit strong anti-tumor activity and improved therapeutic index compared to native IL12 agents
Cancer Research · 2021 · DOI

About the field of Biology

3,752researchers 51,546publications 942,318citations 4.1average h-index

Common research topics in this field:

Genomics and Phylogenetic StudiesPlant-Microbe Interactions and ImmunityPlant tissue culture and regenerationPlant Diversity and EvolutionPlant and animal studiesPlant and Fungal Species Descriptions

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