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Hoang N. Nguyen

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An h-index of 15 places this researcher in Medicine and Pharmacy, within the top 5% of 6,619 profiles in this field in our directory.

Featured publications

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease259 citations
Science Translational Medicine · 2022 · DOI
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic239 citations
Cell · 2021 · DOI
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models228 citations
Nature Neuroscience · 2023 · DOI
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice212 citations
Science Translational Medicine · 2020 · DOI
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia127 citations
Molecular Neurodegeneration · 2022 · DOI
CD98hc is a target for brain delivery of biotherapeutics95 citations
Nature Communications · 2023 · DOI
Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme89 citations
The Journal of Experimental Medicine · 2021 · DOI
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes88 citations
Cell · 2024 · DOI
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab1060 citations
Scientific Reports · 2021 · DOI
Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA53 citations
Science · 2025 · DOI

About the field of Medicine and Pharmacy

Common research topics in this field:

Mosquito-borne diseases and controlAntibiotic Resistance in BacteriaTuberculosis Research and EpidemiologyMalaria Research and ControlCOVID-19 and Mental HealthHIV/AIDS Research and Interventions

Institutions with the most researchers in this field:

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The publication list above is compiled from the open academic database OpenAlex (CC0 licence). Compare with the source record on OpenAlex ↗

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Hoang N. NguyenVietnam Military Medical University
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